PTGDS Polyclonal Antibody

Background:
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.

Research Area: Cancer, Signal Transduction

Synonyms:
PTGDS, L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2

Immunogen: Recombinant fusion protein of human PTGDS (NP_000945.3).

Swissprot: P41222
Gene ID: 5730

Calculated MW: 21 kDa
Observed MW: 33 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.