PTGER4 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses.

Research Area: Signal Transduction

Synonyms:
EP 4, EP4, EP4R, MGC126583, PE2R4, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostaglandin E receptor 4, Prostaglandin E receptor 4 subtype EP4, Prostaglandin E2 receptor, Prostaglandin E2 receptor EP4 subtype, Prostanoid EP4 receptor, PTGER 2, PTGER 4, PTGER2, PTGER4

Immunogen: Synthetic peptide of human PTGER4

Swissprot: P35408
Gene Accession: NP_000949

Calculated MW: 53 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-16022/sc-20677