PTGS1 polyclonal, anti-human, mouse, rat

Background:
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.

Synonyms: COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS

Cellular Location: Endoplasmic reticulum membrane Microsome membrane Peripheral membrane protein

Immunogen:
Recombinant protein of human PTGS1

Gene Symbol: PTGS1

Gene ID: 5742

Swiss prot: P23219

Calculated MW: 69kDa

Recommended dilution:
WB 1:500-2000, IHC 1:100-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.