PTGS1 polyclonal (C-term), anti-human

PTGS1 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP2827b
Catalog Number: AC-AP2827b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB17407
Applications: WB, IHC-P, IF
Datasheet

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Background:
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis.

Other Names:
Prostaglandin G/H synthase 1, Cyclooxygenase-1, COX-1, Prostaglandin H2 synthase 1, PGH synthase 1, PGHS-1, PHS 1, Prostaglandin-endoperoxide synthase 1, PTGS1, COX1

Target/Specificity:
This PTGS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 571-599 amino acids from the C-terminal region of human PTGS1.

Antigen Region:
571-599

Antigen Type: Synthetic Peptide

Gene Name: PTGS1 (HGNC:9604)
Gene ID: 5742
Primary Accession: P23219
NCBI Accession: NP_000953.2;NP_001258094.1;NP_001258095.1;NP_001258297.1;NP_542158.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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