PTGS2 Antibody (Center H193) Blocking peptide
€363.00
In stock
SKU
AC-BP14091c
Background:
Prostaglandin-endoperoxide synthase (PTGS), also known ascyclooxygenase, is the key enzyme in prostaglandin biosynthesis,and acts both as a dioxygenase and as a peroxidase. There are twoisozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2,which differ in their regulation of expression and tissuedistribution. This gene encodes the inducible isozyme. It isregulated by specific stimulatory events, suggesting that it isresponsible for the prostanoid biosynthesis involved ininflammation and mitogenesis.
Other Names:
Prostaglandin G/H synthase 2, Cyclooxygenase-2, COX-2, PHS II, Prostaglandin H2 synthase 2, PGH synthase 2, PGHS-2, Prostaglandin-endoperoxide synthase 2, PTGS2, COX2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14091c was selected from the Center H193 region of PTGS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PTGS2 (HGNC:9605)
Gene ID: 5743
Primary Accession: P35354
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Prostaglandin-endoperoxide synthase (PTGS), also known ascyclooxygenase, is the key enzyme in prostaglandin biosynthesis,and acts both as a dioxygenase and as a peroxidase. There are twoisozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2,which differ in their regulation of expression and tissuedistribution. This gene encodes the inducible isozyme. It isregulated by specific stimulatory events, suggesting that it isresponsible for the prostanoid biosynthesis involved ininflammation and mitogenesis.
Other Names:
Prostaglandin G/H synthase 2, Cyclooxygenase-2, COX-2, PHS II, Prostaglandin H2 synthase 2, PGH synthase 2, PGHS-2, Prostaglandin-endoperoxide synthase 2, PTGS2, COX2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14091c was selected from the Center H193 region of PTGS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PTGS2 (HGNC:9605)
Gene ID: 5743
Primary Accession: P35354
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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