PTGS2 monoclonal, anti-human
€0.00
In stock
SKU
AC-AM8711b
Catalog Number: AC-AM8711b
Size: 50 µl, 200 µl
Isotype: mouse IgG1,κ
Clone Name: 2104CT1721.122.37
Applications: WB
Datasheet
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Size: 50 µl, 200 µl
Isotype: mouse IgG1,κ
Clone Name: 2104CT1721.122.37
Applications: WB
Datasheet
Request Information
Background:
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
Other Names:
Prostaglandin G/H synthase 2, 1.14.99.1, Cyclooxygenase-2, COX-2, PHS II, Prostaglandin H2 synthase 2, PGH synthase 2, PGHS-2, Prostaglandin-endoperoxide synthase 2, PTGS2, COX2
Target/Specificity:
This PTGS2 antibody is generated from a mouse immunized with a recombiant protein from the human region of human PTGS2.
Antigen Type: Synthesized Peptide
Gene Name: PTGS2 (HGNC:9605)
Gene ID: 5743
Primary Accession: P35354
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
Other Names:
Prostaglandin G/H synthase 2, 1.14.99.1, Cyclooxygenase-2, COX-2, PHS II, Prostaglandin H2 synthase 2, PGH synthase 2, PGHS-2, Prostaglandin-endoperoxide synthase 2, PTGS2, COX2
Target/Specificity:
This PTGS2 antibody is generated from a mouse immunized with a recombiant protein from the human region of human PTGS2.
Antigen Type: Synthesized Peptide
Gene Name: PTGS2 (HGNC:9605)
Gene ID: 5743
Primary Accession: P35354
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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