PTGS2 polyclonal, anti-human, mouse, rat

Background:
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

Synonyms: COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2

Cellular Location: Endoplasmic reticulum membrane Microsome membrane Peripheral membrane protein

Immunogen:
Recombinant protein of human PTGS2

Gene Symbol: PTGS2

Gene ID: 5743

Swiss prot: P35354

Calculated MW: 69kDa

Recommended dilution:
WB 1:1000-4000, IP 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.