PTH1R Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]

Research Area: Cancer, Neuroscience, Signal Transduction

Synonyms:
MGC138426, MGC138452, Parathyroid hormone 1 receptor, Parathyroid hormone/parathyroid hormone related peptide receptor, Parathyroid hormone/parathyroid hormone related protein receptor, Parathyroid hormone/parathyroid hormone-related peptide receptor, PTH receptor, PTH/PTHr receptor, PTH/PTHrP receptor, PTH/PTHrP type I receptor, PTH1 receptor, PTH1R, PTH1R, PTHR 1, PTHR, PTHR1

Immunogen: Fusion protein of human PTH1R

Swissprot: Q03431
Gene Accession: BC031578

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.14 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.