PTHrP polyclonal, anti-human, mouse, rat, rabbit, pig, chicken, bovine

Protein Family: Hormones

Pathway and Disease: Signaling Molecules and Interaction, Endocrine System, Cell Growth and Death

Description:
Parathyroid hormone-related protein (PTHrP) is a neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and is involved in epithelial calcium ion transport. PTHrP regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Defects in PTHrP are the cause of brachydactyly type E2 (BDE2). BDE2 is a form of brachydactyly. Brachydactyly defines a group of inherited malformations characterized by shortening of the digits due to abnormal development of the phalanges and/or the metacarpals.

Alternate Names: PTHrP, Parathyroid hormone-related protein, PTH-rP, PTHLH

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P12272

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PTHrP.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.