PTK6 Polyclonal Antibody

Background:
The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase whicHuman, Mouseay function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Signal Transduction

Synonyms:
Breast tumor kinase, Breast tumour kinase, Protein tyrosine kinase 6, Protein-tyrosine kinase 6, Ptk6, PTK6, Tyrosine protein kinase BRK, Tyrosine-protein kinase BRK

Immunogen: Recombinant protein of human PTK6

Swissprot: Q13882
Gene Accession: BC035843

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-915