PTP gamma polyclonal (Center), anti-human, mouse
€0.00
In stock
SKU
AC-AP8414a
Catalog Number: AC-AP8414a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB0553
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB0553
Applications: WB
Datasheet
Request Information
Background:
PTPgamma is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. The gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.
Other Names:
Receptor-type tyrosine-protein phosphatase gamma, Protein-tyrosine phosphatase gamma, R-PTP-gamma, PTPRG, PTPG
Target/Specificity:
This PTP gamma antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-782 amino acids from the Central region of human PTP gamma.
Antigen Region:
751-782
Antigen Type: Synthetic Peptide
Gene Name: PTPRG
Gene ID: 5793
Primary Accession: P23470
NCBI Accession: NP_002832.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
PTPgamma is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. The gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.
Other Names:
Receptor-type tyrosine-protein phosphatase gamma, Protein-tyrosine phosphatase gamma, R-PTP-gamma, PTPRG, PTPG
Target/Specificity:
This PTP gamma antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-782 amino acids from the Central region of human PTP gamma.
Antigen Region:
751-782
Antigen Type: Synthetic Peptide
Gene Name: PTPRG
Gene ID: 5793
Primary Accession: P23470
NCBI Accession: NP_002832.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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