PTPA polyclonal, anti-human, mouse, rat
€469.00
In stock
SKU
252161
Protein Family: Enzymes, Chaperones and Folding Catalysts
Pathway and Disease: Signaling Molecules and Interaction
Description:
Serine/threonine-protein phosphatase 2A activator (PTPA) accelerates the folding of proteins. PTPA catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PTPA acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A), modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of PTPA. PTPA can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg2+.
Alternate Names: Serine/threonine-protein phosphatase 2A activator, Serine/threonine-protein phosphatase 2A regulatory subunit B', PP2A, subunit B', PR53 isoform, Phosphotyrosyl phosphatase activator, PTPA, Serine/threonine-protein phosphatase 2A regulatory subunit 4, PPP2R4, PTPA
Application Notes: E: 1:10,000-1:50,000; WB: 1:200-1:1,000
Accession No.: Q15257
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PTPA.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
Serine/threonine-protein phosphatase 2A activator (PTPA) accelerates the folding of proteins. PTPA catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PTPA acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A), modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of PTPA. PTPA can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg2+.
Alternate Names: Serine/threonine-protein phosphatase 2A activator, Serine/threonine-protein phosphatase 2A regulatory subunit B', PP2A, subunit B', PR53 isoform, Phosphotyrosyl phosphatase activator, PTPA, Serine/threonine-protein phosphatase 2A regulatory subunit 4, PPP2R4, PTPA
Application Notes: E: 1:10,000-1:50,000; WB: 1:200-1:1,000
Accession No.: Q15257
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PTPA.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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