PTPN11 monoclonal, anti-human, mouse
€0.00
In stock
SKU
AC-AM1920b
Catalog Number: AC-AM1920b
Size: 80 µl, 400 µl
Isotype: mouse IgG1,k
Clone Name: 246CT9.8.2
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG1,k
Clone Name: 246CT9.8.2
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
Other Names:
Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, PTP-1D, Protein-tyrosine phosphatase 2C, PTP-2C, SH-PTP2, SHP-2, Shp2, SH-PTP3, PTPN11, PTP2C, SHPTP2
Target/Specificity:
This PTPN11 monoclonal antibody is generated from mouse immunized with PTPN11 recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: PTPN11
Gene ID: 5781
Primary Accession: Q06124
NCBI Accession: NP_002825.3;NP_542168.1
Other Accession: NP_002825.3
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
Other Names:
Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, PTP-1D, Protein-tyrosine phosphatase 2C, PTP-2C, SH-PTP2, SHP-2, Shp2, SH-PTP3, PTPN11, PTP2C, SHPTP2
Target/Specificity:
This PTPN11 monoclonal antibody is generated from mouse immunized with PTPN11 recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: PTPN11
Gene ID: 5781
Primary Accession: Q06124
NCBI Accession: NP_002825.3;NP_542168.1
Other Accession: NP_002825.3
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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