PTPN12 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis.

Research Area: Cancer, Signal Transduction

Synonyms:
Protein tyrosine phosphatase G1, Protein tyrosine phosphatase non receptor type 12, Protein-tyrosine phosphatase G1, PTN12, PTP PEST, PTP-PEST, PTPG1, Ptpn12, Tyrosine protein phosphatase non receptor type 12, Tyrosine-protein phosphatase non-receptor type 12

Immunogen: Synthetic peptide of human PTPN12

Swissprot: Q05209
Gene Accession: NP_001124480

Calculated MW: 88 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-18412/sc-8228/sc-134473