PTPN22 antibody (clone 4F6), anti-human
€435.00
In stock
SKU
AC-AT3493a
Catalog Number: AC-AT3493a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT3493a">Request Information
Background:
This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Other Names:
Tyrosine-protein phosphatase non-receptor type 22, Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, Lymphoid phosphatase, LyP, PEST-domain phosphatase, PEP, PTPN22, PTPN8
Antigen Type:
Recombinant Protein
Gene Name: PTPN22
Gene ID: 26191
NCBI Accession: NP_001180360.1;NP_036543.4;NP_057051.3
Primary Accession: Q9Y2R2
Other Accession: BC017785
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Other Names:
Tyrosine-protein phosphatase non-receptor type 22, Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, Lymphoid phosphatase, LyP, PEST-domain phosphatase, PEP, PTPN22, PTPN8
Antigen Type:
Recombinant Protein
Gene Name: PTPN22
Gene ID: 26191
NCBI Accession: NP_001180360.1;NP_036543.4;NP_057051.3
Primary Accession: Q9Y2R2
Other Accession: BC017785
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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