PTPRS antibody (clone 1H6), anti-human
€435.00
In stock
SKU
AC-AT3497a
Catalog Number: AC-AT3497a
Size: 100 µg
Isotype: mouse IgG2b kappa
Applications: WB
Request Information AC-AT3497a">Request Information
Size: 100 µg
Isotype: mouse IgG2b kappa
Applications: WB
Request Information AC-AT3497a">Request Information
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
Other Names:
Receptor-type tyrosine-protein phosphatase S, R-PTP-S, Receptor-type tyrosine-protein phosphatase sigma, R-PTP-sigma, PTPRS
Antigen Type:
Recombinant Protein
Gene Name: PTPRS
Gene ID: 5802
NCBI Accession: NP_002841.3;NP_570923.2;NP_570924.2;NP_570925.2
Primary Accession: Q13332
Other Accession: BC029496
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
Other Names:
Receptor-type tyrosine-protein phosphatase S, R-PTP-S, Receptor-type tyrosine-protein phosphatase sigma, R-PTP-sigma, PTPRS
Antigen Type:
Recombinant Protein
Gene Name: PTPRS
Gene ID: 5802
NCBI Accession: NP_002841.3;NP_570923.2;NP_570924.2;NP_570925.2
Primary Accession: Q13332
Other Accession: BC029496
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review