PTPRU (PTP-U) Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP8418a
Background:
PTPlambda, a member of the receptor class 2B subfamily of protein-tyrosine phosophatases, is involved in regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. It forms complexes with beta-catenin and gamma-catenin/plakoglobin. This Type I membrane protein is found at high levels in brain, pancreas, and skeletal muscle; less in colon, kidney, liver, stomach, and uterus; no expression is observed in placenta and spleen. PTPlambda is up-regulated upon cell contact. The protein contains 4 fibronectin type III domains, 1 immunoglobulin-like C2-type domain, 1 MAM domain, and 2 protein-tyrosine phosphatase domains.
Other Names:
Receptor-type tyrosine-protein phosphatase U, R-PTP-U, Pancreatic carcinoma phosphatase 2, PCP-2, Protein-tyrosine phosphatase J, PTP-J, hPTP-J, Protein-tyrosine phosphatase pi, PTP pi, Protein-tyrosine phosphatase receptor omicron, PTP-RO, Receptor-type protein-tyrosine phosphatase psi, R-PTP-psi, PTPRU, FMI, PCP2, PTPRO
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8418a was selected from the N-term region of human PTPlambda . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PTPRU
Gene ID: 10076
Primary Accession: Q92729
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
PTPlambda, a member of the receptor class 2B subfamily of protein-tyrosine phosophatases, is involved in regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. It forms complexes with beta-catenin and gamma-catenin/plakoglobin. This Type I membrane protein is found at high levels in brain, pancreas, and skeletal muscle; less in colon, kidney, liver, stomach, and uterus; no expression is observed in placenta and spleen. PTPlambda is up-regulated upon cell contact. The protein contains 4 fibronectin type III domains, 1 immunoglobulin-like C2-type domain, 1 MAM domain, and 2 protein-tyrosine phosphatase domains.
Other Names:
Receptor-type tyrosine-protein phosphatase U, R-PTP-U, Pancreatic carcinoma phosphatase 2, PCP-2, Protein-tyrosine phosphatase J, PTP-J, hPTP-J, Protein-tyrosine phosphatase pi, PTP pi, Protein-tyrosine phosphatase receptor omicron, PTP-RO, Receptor-type protein-tyrosine phosphatase psi, R-PTP-psi, PTPRU, FMI, PCP2, PTPRO
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8418a was selected from the N-term region of human PTPlambda . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PTPRU
Gene ID: 10076
Primary Accession: Q92729
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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