PUS10 Blocking Peptide (N-term)

Background:
Pseudouridination, the isomerization of uridine topseudouridine, is the most common posttranscriptional nucleotidemodification found in RNA and is essential for biologic functionssuch as spliceosome biogenesis. Pseudouridylate synthases, such asPUS10, catalyze pseudouridination of structural RNAs, includingtransfer, ribosomal, and splicing RNAs. These enzymes also act asRNA chaperones, facilitating the correct folding and assembly oftRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied byOMIM].

Other Names:
Putative tRNA pseudouridine synthase Pus10, 5499-, Coiled-coil domain-containing protein 139, tRNA pseudouridine 55 synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase, PUS10, CCDC139, DOBI

Target/Specificity:
The synthetic peptide sequence is selected from aa 67-78 of HUMAN PUS10

Gene Name: PUS10 (HGNC:26505)

Gene ID: 150962
Primary Accession: Q3MIT2
Other Accession: NP_653310.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.