PVR Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6260a
Background:
The poliovirus receptor (PVR) is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. PVR is involved in intercellular adhesion and its cytoplasmic domain may target endocytic vesicles to the microtubular network. The extracellular domain of PVR mediates cell attachment to the extracellular matrix molecule vitronectin, while its cytoplasmic domain interacts with the dynein light chain Tctex-1. PVR is a primate-restricted protein expressed during development in mesenchymal tissues and ventrally derived structures within the CNS. Its exact biological function remains to be determined; it is reported that PVR is aberrantly expressed in tumors of neuroectodermal origin.
Other Names:
Poliovirus receptor, Nectin-like protein 5, NECL-5, CD155, PVR, PVS
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6260a was selected from the C-term region of human PVR . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PVR
Gene ID: 5817
Primary Accession: P15151
Other Accession: PVR_HUMAN
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The poliovirus receptor (PVR) is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. PVR is involved in intercellular adhesion and its cytoplasmic domain may target endocytic vesicles to the microtubular network. The extracellular domain of PVR mediates cell attachment to the extracellular matrix molecule vitronectin, while its cytoplasmic domain interacts with the dynein light chain Tctex-1. PVR is a primate-restricted protein expressed during development in mesenchymal tissues and ventrally derived structures within the CNS. Its exact biological function remains to be determined; it is reported that PVR is aberrantly expressed in tumors of neuroectodermal origin.
Other Names:
Poliovirus receptor, Nectin-like protein 5, NECL-5, CD155, PVR, PVS
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6260a was selected from the C-term region of human PVR . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PVR
Gene ID: 5817
Primary Accession: P15151
Other Accession: PVR_HUMAN
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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