PVRL1 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP14522b
Background:
This gene encodes an adhesion protein that plays a role inthe organization of adherens junctions and tight junctions inepithelial and endothelial cells. The protein is acalcium(2+)-independent cell-cell adhesion molecule that belongs tothe immunoglobulin superfamily and has 3 extracellularimmunoglobulin-like loops, a single transmembrane domain (in someisoforms), and a cytoplasmic region. This protein acts as areceptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2(HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viralentry into epithelial and neuronal cells. Mutations in this genecause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1)as well as non-syndromic cleft lip with or without cleft palate(CL/P). Alternative splicing results in multiple transcriptvariants encoding proteins with distinct C-termini. [provided byRefSeq].
Other Names:
Nectin-1, Herpes virus entry mediator C, Herpesvirus entry mediator C, HveC, Herpesvirus Ig-like receptor, HIgR, Poliovirus receptor-related protein 1, CD111, PVRL1, HVEC, PRR1
Gene Name: NECTIN1 (HGNC:9706)
Gene ID: 5818
Primary Accession: Q15223
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes an adhesion protein that plays a role inthe organization of adherens junctions and tight junctions inepithelial and endothelial cells. The protein is acalcium(2+)-independent cell-cell adhesion molecule that belongs tothe immunoglobulin superfamily and has 3 extracellularimmunoglobulin-like loops, a single transmembrane domain (in someisoforms), and a cytoplasmic region. This protein acts as areceptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2(HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viralentry into epithelial and neuronal cells. Mutations in this genecause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1)as well as non-syndromic cleft lip with or without cleft palate(CL/P). Alternative splicing results in multiple transcriptvariants encoding proteins with distinct C-termini. [provided byRefSeq].
Other Names:
Nectin-1, Herpes virus entry mediator C, Herpesvirus entry mediator C, HveC, Herpesvirus Ig-like receptor, HIgR, Poliovirus receptor-related protein 1, CD111, PVRL1, HVEC, PRR1
Gene Name: NECTIN1 (HGNC:9706)
Gene ID: 5818
Primary Accession: Q15223
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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