PYK2 (phospho-Y580) polyclonal, anti-human, mouse, rat
€328.00
In stock
SKU
BS4247
Background:
Pyk2 is a protein tyrosine kinase related to Focal Adhesion Kinase (p125 FAK). Pyk2 is highly expressed in the central nervous system. It is phosphorylated on tyrosine residues in response to various stimuli that elevate intracellular calcium concentration, as well as by protein kinase C activation.
Alternative Name:
Cell adhesion kinase beta, CAK beta, Calcium-dependent tyrosine kinase, CADTK, Related adhesion focal tyrosine kinase, RAFTK, PYK2, FAK2, PYK2, RAFTK
Application Dilution: IHC: 1:50~1:200
Specificity: p-PYK2 (Y580) polyclonal antibody detects endogenous levels of PYK2 protein only when phosphorylated at Tyr580.
Immunogen:
Synthetic phosphopeptide derived from human PYK2 around the phosphorylation site of Tyrosine 580.
MW: ~ 116 kDa
Swis Prot.: Q14289
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Pyk2 is a protein tyrosine kinase related to Focal Adhesion Kinase (p125 FAK). Pyk2 is highly expressed in the central nervous system. It is phosphorylated on tyrosine residues in response to various stimuli that elevate intracellular calcium concentration, as well as by protein kinase C activation.
Alternative Name:
Cell adhesion kinase beta, CAK beta, Calcium-dependent tyrosine kinase, CADTK, Related adhesion focal tyrosine kinase, RAFTK, PYK2, FAK2, PYK2, RAFTK
Application Dilution: IHC: 1:50~1:200
Specificity: p-PYK2 (Y580) polyclonal antibody detects endogenous levels of PYK2 protein only when phosphorylated at Tyr580.
Immunogen:
Synthetic phosphopeptide derived from human PYK2 around the phosphorylation site of Tyrosine 580.
MW: ~ 116 kDa
Swis Prot.: Q14289
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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