QARS antibody (clone 5F5), anti-human
€435.00
In stock
SKU
AC-AT3506a
Catalog Number: AC-AT3506a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IHC, IP, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IHC, IP, E
Request Information AC-AT3506a">Request Information
Background:
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.
Other Names:
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS, QARS
Antigen Type:
Recombinant Protein
Gene Name: QARS1 (HGNC:9751)
Gene ID: 5859
NCBI Accession: NP_001259002.1;NP_005042.1
Primary Accession: P47897
Other Accession: NM_005051
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.
Other Names:
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS, QARS
Antigen Type:
Recombinant Protein
Gene Name: QARS1 (HGNC:9751)
Gene ID: 5859
NCBI Accession: NP_001259002.1;NP_005042.1
Primary Accession: P47897
Other Accession: NM_005051
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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