QPRT antibody (clone 5D11), anti-human
€435.00
In stock
SKU
AC-AT3509a
Catalog Number: AC-AT3509a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, E
Request Information AC-AT3509a">Request Information
Background:
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.
Other Names:
Nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase, QPRTase, QPRT
Antigen Type:
Recombinant Protein
Gene Name: QPRT
Gene ID: 23475
NCBI Accession: NP_055113.2
Primary Accession: Q15274
Other Accession: NM_014298
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.
Other Names:
Nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase, QPRTase, QPRT
Antigen Type:
Recombinant Protein
Gene Name: QPRT
Gene ID: 23475
NCBI Accession: NP_055113.2
Primary Accession: Q15274
Other Accession: NM_014298
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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