RAB11B Picoband™ (clone 6C5), anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO14921
Catalog Number: AC-ABO14921
Size: 100 µg
Isotype: Mouse
Applications: WB, IF, ICC, FC
Datasheet
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Size: 100 µg
Isotype: Mouse
Applications: WB, IF, ICC, FC
Datasheet
Request Information
Description: Anti-RAB11B Antibody Picoband™ (monoclonal, 6C5) . Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.Protein Name: Ras-related protein Rab-11B
Protein Function:
The small GTPases Rab are key regulators of intracellular membrane trafficking,from the formation of transport vesicles to their fusion with membranes.Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation,movement,tethering and fusion.That Rab plays a role in endocytic recycling,regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR,epithelial sodium channel/ENaC,potassium voltage- gated channel,and voltage-dependent L-type calcium channel.May also regulate constitutive and regulated secretion,like insulin granule exocytosis.Required for melanosome transport and release from melanocytes.Also regulates V-ATPase intracellular transport in response to extracellular acidosis.
Other Names: Ras-related protein Rab-11B, 3.6.5.2, GTP-binding protein YPT3, RAB11B, YPT3
Clone Name(s):
Clone: 6C5
Subcellular Localization: Recycling endosome membrane;Lipid-anchor;Cytoplasmic side.Cytoplasmic vesicle,secretory vesicle,synaptic vesicle membrane;Lipid-anchor;Cytoplasmic side.Cytoplasmic vesicle,phagosome membrane;Lipid-anchor;Cytoplasmic side.Recruited to phagosomes containing S.aureus.
Gene ID: 9230
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human RAB11B, which shares 97.4% and 100% amino acid (aa) sequence identity with mouse and rat RAB11B, respectively.
Calculated MW: 24489
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500 µg/ml.
Contents: "Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Protein Function:
The small GTPases Rab are key regulators of intracellular membrane trafficking,from the formation of transport vesicles to their fusion with membranes.Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation,movement,tethering and fusion.That Rab plays a role in endocytic recycling,regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR,epithelial sodium channel/ENaC,potassium voltage- gated channel,and voltage-dependent L-type calcium channel.May also regulate constitutive and regulated secretion,like insulin granule exocytosis.Required for melanosome transport and release from melanocytes.Also regulates V-ATPase intracellular transport in response to extracellular acidosis.
Other Names: Ras-related protein Rab-11B, 3.6.5.2, GTP-binding protein YPT3, RAB11B, YPT3
Clone Name(s):
Clone: 6C5
Subcellular Localization: Recycling endosome membrane;Lipid-anchor;Cytoplasmic side.Cytoplasmic vesicle,secretory vesicle,synaptic vesicle membrane;Lipid-anchor;Cytoplasmic side.Cytoplasmic vesicle,phagosome membrane;Lipid-anchor;Cytoplasmic side.Recruited to phagosomes containing S.aureus.
Gene ID: 9230
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human RAB11B, which shares 97.4% and 100% amino acid (aa) sequence identity with mouse and rat RAB11B, respectively.
Calculated MW: 24489
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500 µg/ml.
Contents: "Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
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