Rab14 (7A6 (clone 7A6-4H9-7H10), anti-human

Background:
Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 shedding and cell-cell adhesion.

Synonyms: Ras-related protein Rab-14, RAB14

Cellular Location: Cytoplasmic vesicle, Endosome, Golgi apparatus, Membrane

Immunogen:
Recombinant protein of human RAB14

Gene Symbol: Rab14

Gene ID: 51552

Swiss prot: P61106

Calculated MW: 24kDa

Recommended dilution:
WB 1:2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.