RAB31 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5875
Background:
The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies all of which are thought to play an important role in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 31, also known as RAB22B, is a 194 amino lipid-anchored protein that localizes to the cytoplasmic side of the cell membrane and belongs to the Ras-related GTPase superfamily. Expressed at high levels in lung, brain and heart, Rab 31 may function in a similar manner to other Rab proteins, namely playing a role in protein transport.
Alternative Name:
Ras-related protein Rab-31, Ras-related protein Rab-22B, RAB31, RAB22B
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: RAB31 polyclonal antibody detects endogenous levels of RAB31 protein.
Immunogen:
Synthetic peptide, corresponding to the 121-166 of Human RAB31.
MW: ~ 22 kDa
Swis Prot.: Q13636
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies all of which are thought to play an important role in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 31, also known as RAB22B, is a 194 amino lipid-anchored protein that localizes to the cytoplasmic side of the cell membrane and belongs to the Ras-related GTPase superfamily. Expressed at high levels in lung, brain and heart, Rab 31 may function in a similar manner to other Rab proteins, namely playing a role in protein transport.
Alternative Name:
Ras-related protein Rab-31, Ras-related protein Rab-22B, RAB31, RAB22B
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: RAB31 polyclonal antibody detects endogenous levels of RAB31 protein.
Immunogen:
Synthetic peptide, corresponding to the 121-166 of Human RAB31.
MW: ~ 22 kDa
Swis Prot.: Q13636
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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