RAB33A polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5876
Background:
The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 33B and Rab 33A share conserved effector domains, but share only 55.3% overall amino acid identity. This suggests that Rab 33B and Rab 33A may interact with similar effector and regulatory proteins.
Alternative Name:
Ras-related protein Rab-33A, Small GTP-binding protein S10, RAB 33A, RABS10
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: RAB33A polyclonal antibody detects endogenous levels of RAB33A protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 173-218 of Human RAB33A.
MW: ~ 27 kDa
Swis Prot.: Q14088
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 33B and Rab 33A share conserved effector domains, but share only 55.3% overall amino acid identity. This suggests that Rab 33B and Rab 33A may interact with similar effector and regulatory proteins.
Alternative Name:
Ras-related protein Rab-33A, Small GTP-binding protein S10, RAB 33A, RABS10
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: RAB33A polyclonal antibody detects endogenous levels of RAB33A protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 173-218 of Human RAB33A.
MW: ~ 27 kDa
Swis Prot.: Q14088
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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