RAB41 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61254
Background:
Rab 41 (Ras-related protein Rab-41) is a 222 amino acid protein that belongs to the small GTPase superfamily and the Rab family.Members of the Rab familyfunction asregulators ofmembrane trafficking. Theycycle between inactive GDP-bound and activated GTP-bound states,which iscontrolled by GTP hydrolysis-activating proteins(GAPs). Rab 41 can be activated bythe GAP protein RN-Tre.Localizing to the Golgicomplex, Rab 41 isinvolved in protein transport and participatesin GTP binding. Existing astwo alternativelyspliced isoforms, the gene that encodesthe Rab 41 proteinmapsto human chromosome Xq13.1. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. Color blindness, hemophilia, and Duchennemuscular dystrophy arewellknown X chromosome-linked conditionswhich affectmales more frequently asmalescarry a single X chromosome.
Alternative Name:
Ras-related protein Rab-41, RAB41
Application Dilution: WB: 1:500~1:1000
Specificity: RAB41 polyclonal antibody detects endogenous levels of RAB41 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human RAB41.
MW: ~ 25 kDa
Swis Prot.: Q5JT25
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Rab 41 (Ras-related protein Rab-41) is a 222 amino acid protein that belongs to the small GTPase superfamily and the Rab family.Members of the Rab familyfunction asregulators ofmembrane trafficking. Theycycle between inactive GDP-bound and activated GTP-bound states,which iscontrolled by GTP hydrolysis-activating proteins(GAPs). Rab 41 can be activated bythe GAP protein RN-Tre.Localizing to the Golgicomplex, Rab 41 isinvolved in protein transport and participatesin GTP binding. Existing astwo alternativelyspliced isoforms, the gene that encodesthe Rab 41 proteinmapsto human chromosome Xq13.1. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. Color blindness, hemophilia, and Duchennemuscular dystrophy arewellknown X chromosome-linked conditionswhich affectmales more frequently asmalescarry a single X chromosome.
Alternative Name:
Ras-related protein Rab-41, RAB41
Application Dilution: WB: 1:500~1:1000
Specificity: RAB41 polyclonal antibody detects endogenous levels of RAB41 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human RAB41.
MW: ~ 25 kDa
Swis Prot.: Q5JT25
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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