Rab5 RAB5A monoclonal, anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO13383
Catalog Number: AC-ABO13383
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC
Datasheet
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Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC
Datasheet
Request Information
Description: Anti-Rab5 RAB5A Rabbit Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Protein Function:
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension..
Other Names: Ras-related protein Rab-5A, 3.6.5.2, RAB5A, RAB5
Clone Name(s):
Clone: EOE-18
Subcellular Localization: Cell membrane ; Lipid-anchor ; Cytoplasmic side. Early endosome membrane ; Lipid-anchor. Melanosome. Cytoplasmic vesicle. Cell projection, ruffle. Membrane. Cytoplasm, cytosol. Enriched in stage I melanosomes. Alternates between membrane-bound and cytosolic forms.
Gene ID: 5868
Immunogen: A synthesized peptide derived from human Rab5
Calculated MW: 23659
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Function:
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension..
Other Names: Ras-related protein Rab-5A, 3.6.5.2, RAB5A, RAB5
Clone Name(s):
Clone: EOE-18
Subcellular Localization: Cell membrane ; Lipid-anchor ; Cytoplasmic side. Early endosome membrane ; Lipid-anchor. Melanosome. Cytoplasmic vesicle. Cell projection, ruffle. Membrane. Cytoplasm, cytosol. Enriched in stage I melanosomes. Alternates between membrane-bound and cytosolic forms.
Gene ID: 5868
Immunogen: A synthesized peptide derived from human Rab5
Calculated MW: 23659
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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