RAD18 antibody (clone 2B9), anti-human, rat
€435.00
In stock
SKU
AC-AT3546a
Catalog Number: AC-AT3546a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IFhttps://www.abcepta.com/products/pdf_download/AT3546a-RAD18-Antibody-monoclonal-M03">Request Information AC-AT3546a">Request Information
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IFhttps://www.abcepta.com/products/pdf_download/AT3546a-RAD18-Antibody-monoclonal-M03">Request Information AC-AT3546a">Request Information
Background:
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
Other Names:
E3 ubiquitin-protein ligase RAD18, 632-, Postreplication repair protein RAD18, hHR18, hRAD18, RING finger protein 73, RAD18, RNF73
Antigen Type:
Recombinant Protein
Gene Name: RAD18
Gene ID: 56852
NCBI Accession: NP_064550.3
Primary Accession: Q9NS91
Other Accession: NM_020165
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
Other Names:
E3 ubiquitin-protein ligase RAD18, 632-, Postreplication repair protein RAD18, hHR18, hRAD18, RING finger protein 73, RAD18, RNF73
Antigen Type:
Recombinant Protein
Gene Name: RAD18
Gene ID: 56852
NCBI Accession: NP_064550.3
Primary Accession: Q9NS91
Other Accession: NM_020165
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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