RAD21 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP7396b
Background:
RAD21 is highly similar to the gene product of Schizosaccharomyces pombe rad21, a protein involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
Other Names:
Double-strand-break repair protein rad21 homolog, hHR21, Nuclear matrix protein 1, NXP-1, SCC1 homolog, RAD21, HR21, KIAA0078, NXP1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7396b was selected from the C-term region of human RAD21. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: RAD21
Gene ID: 5885
Primary Accession: O60216
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
RAD21 is highly similar to the gene product of Schizosaccharomyces pombe rad21, a protein involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
Other Names:
Double-strand-break repair protein rad21 homolog, hHR21, Nuclear matrix protein 1, NXP-1, SCC1 homolog, RAD21, HR21, KIAA0078, NXP1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7396b was selected from the C-term region of human RAD21. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: RAD21
Gene ID: 5885
Primary Accession: O60216
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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