Rad51 (L302) polyclonal, anti-human, mouse
€305.00
In stock
SKU
BS3771
Background:
Rad51 is a recombinase that is essential for homologous recombination and double-strand break repair. It binds to single and double-stranded DNA, and has DNA-dependent ATPase activity. Rad51 unwinds duplex DNA and forms helical nucleoprotein filaments in a manner that is controlled through the action of DNA helicases that counteract nucleofilament formation. Rad51 interacts with BRCA1 and BRCA2, and also plays a role in p53-mediated signalling. Interaction of Rad51 with Chk1 kinase may occur in response to Chk1 phosphorylation
Alternative Name:
BRCC5, DNA repair protein RAD51 homolog 1, E coli RecA homolog, HGNC:9817, HRAD51, Homolog of E coli RecA, HsRad51, HsT16930, RAD51 S cerevisiae homolog, RAD51 homolog S. cerevisiae, RAD51A, RECA, Rad 51, RecA homolog E. coli, RecA like protein,
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: Rad51 (L302) polyclonal antibody detects endogenous levels of Rad51 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 280-330 of Human Rad51.
MW: ~ 42 kDa
Swis Prot.: Q06609
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Rad51 is a recombinase that is essential for homologous recombination and double-strand break repair. It binds to single and double-stranded DNA, and has DNA-dependent ATPase activity. Rad51 unwinds duplex DNA and forms helical nucleoprotein filaments in a manner that is controlled through the action of DNA helicases that counteract nucleofilament formation. Rad51 interacts with BRCA1 and BRCA2, and also plays a role in p53-mediated signalling. Interaction of Rad51 with Chk1 kinase may occur in response to Chk1 phosphorylation
Alternative Name:
BRCC5, DNA repair protein RAD51 homolog 1, E coli RecA homolog, HGNC:9817, HRAD51, Homolog of E coli RecA, HsRad51, HsT16930, RAD51 S cerevisiae homolog, RAD51 homolog S. cerevisiae, RAD51A, RECA, Rad 51, RecA homolog E. coli, RecA like protein,
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: Rad51 (L302) polyclonal antibody detects endogenous levels of Rad51 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 280-330 of Human Rad51.
MW: ~ 42 kDa
Swis Prot.: Q06609
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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