RAD51C antibody (clone 3F3-5C6), anti-human
€435.00
In stock
SKU
AC-AT3549a
Catalog Number: AC-AT3549a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IF, E
Request Information AC-AT3549a">Request Information
Background:
This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified. [provided by RefSeq]
Other Names:
DNA repair protein RAD51 homolog 3, R51H3, RAD51 homolog C, RAD51-like protein 2, RAD51C, RAD51L2
Antigen Type:
Recombinant Protein
Gene Name: RAD51C
Gene ID: 5889
NCBI Accession: NP_002867.1;NP_478123.1
Primary Accession: O43502
Other Accession: BC000667
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified. [provided by RefSeq]
Other Names:
DNA repair protein RAD51 homolog 3, R51H3, RAD51 homolog C, RAD51-like protein 2, RAD51C, RAD51L2
Antigen Type:
Recombinant Protein
Gene Name: RAD51C
Gene ID: 5889
NCBI Accession: NP_002867.1;NP_478123.1
Primary Accession: O43502
Other Accession: BC000667
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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