RAET1E Antibody(Center) Blocking peptide
€363.00
In stock
SKU
AC-BP19552c
Background:
Members of the RAET1 family, such as RAET1E, are majorhistocompatibility complex (MHC) class I-related genes locatedwithin a 180-kb cluster on chromosome 6q24.2-q25.3. RAET1 proteinscontain MHC class I-like alpha-1 and alpha-2 domains. RAET1E andRAET1G (MIM 609244) differ from the other RAET1 proteins (e.g.,RAET1I, or ULBP1; MIM 605697) in that they have type Imembrane-spanning sequences at their C termini rather thanglycosylphosphatidylinositol anchor sequences. RAET1E is a ligandfor NKG2D (KLRK1; MIM 611817), which is expressed on the surface ofseveral types of immune cells and is involved in innate andadaptive immune responses (summary by Radosavljevic et al. (2002)[PubMed 11827464] and Cao et al. (2007) [PubMed17470428]).
Other Names:
NKG2D ligand 4, N2DL-4, NKG2DL4, Lymphocyte effector toxicity activation ligand, RAE-1-like transcript 4, RL-4, Retinoic acid early transcript 1E, RAET1E, LETAL, N2DL4, ULBP4
Gene Name: RAET1E {ECO:0000303|PubMed:11827464, ECO:0000312|HGNC:HGNC:16793}
Gene ID: 135250
Primary Accession: Q8TD07
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Members of the RAET1 family, such as RAET1E, are majorhistocompatibility complex (MHC) class I-related genes locatedwithin a 180-kb cluster on chromosome 6q24.2-q25.3. RAET1 proteinscontain MHC class I-like alpha-1 and alpha-2 domains. RAET1E andRAET1G (MIM 609244) differ from the other RAET1 proteins (e.g.,RAET1I, or ULBP1; MIM 605697) in that they have type Imembrane-spanning sequences at their C termini rather thanglycosylphosphatidylinositol anchor sequences. RAET1E is a ligandfor NKG2D (KLRK1; MIM 611817), which is expressed on the surface ofseveral types of immune cells and is involved in innate andadaptive immune responses (summary by Radosavljevic et al. (2002)[PubMed 11827464] and Cao et al. (2007) [PubMed17470428]).
Other Names:
NKG2D ligand 4, N2DL-4, NKG2DL4, Lymphocyte effector toxicity activation ligand, RAE-1-like transcript 4, RL-4, Retinoic acid early transcript 1E, RAET1E, LETAL, N2DL4, ULBP4
Gene Name: RAET1E {ECO:0000303|PubMed:11827464, ECO:0000312|HGNC:HGNC:16793}
Gene ID: 135250
Primary Accession: Q8TD07
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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