RALBP1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6171
Background:
Ral A and Ral B constitute a distinct subfamily of Ras-related GTPases (i.e., GDP/GTP binding proteins). Ral proteins are activated by a unique nucleotide exchange factor, Ral GDS, and deactivated by a distinct GTPase-activating protein. Unlike Ras proteins, Ral A and Ral B fail to induce transformed foci when activated variants are expressed in various recipient cells. A potential downstream target of Ral, designated Ral BP-1, has been shown to contain a Rho-GTPase-activating domain. This Rho-GTPase-activating domain interacts preferentially with the Rho family member Cdc42. A Ras/Ral signaling pathway has been reported to mediate phospholipase D (PLD) activation by v-Src, thus indicating PLD as another downstream target of Ral A.
Alternative Name:
RLIP1, 76 a Ral-interacting protein, 76- a Ral-interacting protein, Dinitrophenyl S-glutathione ATPase, DNP-SG ATPase, Ral-interacting protein 1, RalA-binding protein 1, RalA-binding protein 1, RalBP1, RBP1, RIP1, RLIP1, RLIP76,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: RALBP1 polyclonal antibody detects endogenous levels of RALBP1 protein.
Immunogen:
Recombinant full length Human RALBP1.
MW: ~ 76 kDa
Swis Prot.: Q15311
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Ral A and Ral B constitute a distinct subfamily of Ras-related GTPases (i.e., GDP/GTP binding proteins). Ral proteins are activated by a unique nucleotide exchange factor, Ral GDS, and deactivated by a distinct GTPase-activating protein. Unlike Ras proteins, Ral A and Ral B fail to induce transformed foci when activated variants are expressed in various recipient cells. A potential downstream target of Ral, designated Ral BP-1, has been shown to contain a Rho-GTPase-activating domain. This Rho-GTPase-activating domain interacts preferentially with the Rho family member Cdc42. A Ras/Ral signaling pathway has been reported to mediate phospholipase D (PLD) activation by v-Src, thus indicating PLD as another downstream target of Ral A.
Alternative Name:
RLIP1, 76 a Ral-interacting protein, 76- a Ral-interacting protein, Dinitrophenyl S-glutathione ATPase, DNP-SG ATPase, Ral-interacting protein 1, RalA-binding protein 1, RalA-binding protein 1, RalBP1, RBP1, RIP1, RLIP1, RLIP76,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: RALBP1 polyclonal antibody detects endogenous levels of RALBP1 protein.
Immunogen:
Recombinant full length Human RALBP1.
MW: ~ 76 kDa
Swis Prot.: Q15311
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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