Raly (R103) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS9249
Background:
Raly, also known as hnRNP associated with lethal yellow homolog, autoantigen p542 or heterogeneous nuclear ribonucleoprotein C-like 2 (hnRNPCL2), is a 306 amino acid protein belonging to the RRM HNRPC family. Localized to the nucleus, Raly is thought to be an RNA-binding protein involved in pre-mRNA splicing. Phosphorylated upon DNA damage, Raly has been found to be a subunit of the spliceosome C complex. Raly is also an autoantigen that is crossreactive with an Epstein-Barr virus protein. Raly is expressed at higher levels in pancreas, liver, skeletal muscle, lung, brain, heart and kidney with lower levels found in placenta. Produced by alternative splicing, Raly is expressed as two isoforms.
Alternative Name:
RNA-binding protein Raly, Autoantigen p542, Heterogeneous nuclear ribonucleoprotein C-like 2, hnRNP core protein C-like 2, hnRNP associated with lethal yellow protein homolog, RALY, HNRPCL2, P542
Application Dilution: WB: 1:500~1:1000
Specificity: Raly (R103) polyclonal antibody detects endogenous levels of Raly protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 70-120 of Human Raly.
MW: ~ 32 kDa
Swis Prot.: Q9UKM9
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Raly, also known as hnRNP associated with lethal yellow homolog, autoantigen p542 or heterogeneous nuclear ribonucleoprotein C-like 2 (hnRNPCL2), is a 306 amino acid protein belonging to the RRM HNRPC family. Localized to the nucleus, Raly is thought to be an RNA-binding protein involved in pre-mRNA splicing. Phosphorylated upon DNA damage, Raly has been found to be a subunit of the spliceosome C complex. Raly is also an autoantigen that is crossreactive with an Epstein-Barr virus protein. Raly is expressed at higher levels in pancreas, liver, skeletal muscle, lung, brain, heart and kidney with lower levels found in placenta. Produced by alternative splicing, Raly is expressed as two isoforms.
Alternative Name:
RNA-binding protein Raly, Autoantigen p542, Heterogeneous nuclear ribonucleoprotein C-like 2, hnRNP core protein C-like 2, hnRNP associated with lethal yellow protein homolog, RALY, HNRPCL2, P542
Application Dilution: WB: 1:500~1:1000
Specificity: Raly (R103) polyclonal antibody detects endogenous levels of Raly protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 70-120 of Human Raly.
MW: ~ 32 kDa
Swis Prot.: Q9UKM9
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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