RAMP1 antibody (clone 1F1), anti-human
€435.00
In stock
SKU
AC-AT3558a
Catalog Number: AC-AT3558a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: E
Request Information AC-AT3558a">Request Information
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: E
Request Information AC-AT3558a">Request Information
Background:
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
Other Names:
Receptor activity-modifying protein 1, Calcitonin-receptor-like receptor activity-modifying protein 1, CRLR activity-modifying protein 1, RAMP1
Antigen Type:
Recombinant Protein
Gene Name: RAMP1
Gene ID: 10267
NCBI Accession: NP_005846.1
Primary Accession: O60894
Other Accession: NM_005855
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
Other Names:
Receptor activity-modifying protein 1, Calcitonin-receptor-like receptor activity-modifying protein 1, CRLR activity-modifying protein 1, RAMP1
Antigen Type:
Recombinant Protein
Gene Name: RAMP1
Gene ID: 10267
NCBI Accession: NP_005846.1
Primary Accession: O60894
Other Accession: NM_005855
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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