RAMP3 antibody (clone 1C11), anti-human
€435.00
In stock
SKU
AC-AT3559a
Catalog Number: AC-AT3559a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, E
Request Information AC-AT3559a">Request Information
Background:
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.
Other Names:
Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3, CRLR activity-modifying protein 3, RAMP3
Antigen Type:
Recombinant Protein
Gene Name: RAMP3
Gene ID: 10268
NCBI Accession: NP_005847.1
Primary Accession: O60896
Other Accession: BC022304
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.
Other Names:
Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3, CRLR activity-modifying protein 3, RAMP3
Antigen Type:
Recombinant Protein
Gene Name: RAMP3
Gene ID: 10268
NCBI Accession: NP_005847.1
Primary Accession: O60896
Other Accession: BC022304
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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