RAN polyclonal, anti-human, mouse, monkey
€388.00
In stock
SKU
BS6079
Background:
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
Alternative Name:
Androgen receptor associated protein 24, Androgen receptor-associated protein 24, ARA 24, ARA24, Gsp1, GTP binding nuclear protein RAN, GTP-binding nuclear protein Ran, GTPase Ran, LPS, ran, RAN member RAS oncogene family, RAN, Ras like protein TC4, Ras related nuclear protein, Ras-like protein TC4, Ras-related nuclear protein, RASL2 8, TC 4, TC4,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: RAN polyclonal antibody detects endogenous levels of RAN protein.
Immunogen:
Recombinant full length Human RAN.
MW: ~ 26 kDa
Swis Prot.: P62826
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
Alternative Name:
Androgen receptor associated protein 24, Androgen receptor-associated protein 24, ARA 24, ARA24, Gsp1, GTP binding nuclear protein RAN, GTP-binding nuclear protein Ran, GTPase Ran, LPS, ran, RAN member RAS oncogene family, RAN, Ras like protein TC4, Ras related nuclear protein, Ras-like protein TC4, Ras-related nuclear protein, RASL2 8, TC 4, TC4,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: RAN polyclonal antibody detects endogenous levels of RAN protein.
Immunogen:
Recombinant full length Human RAN.
MW: ~ 26 kDa
Swis Prot.: P62826
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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