RANBP5 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP9108b
Background:
Nucleocytoplasmic transport, a signal- andenergy-dependent process, takes place through nuclear porecomplexes embedded in the nuclear envelope. The import of proteinscontaining a nuclear localization signal (NLS) requires the NLSimport receptor, a heterodimer of importin alpha and beta subunitsalso known as karyopherins. Importin alpha binds the NLS-containingcargo in the cytoplasm and importin beta docks the complex at thecytoplasmic side of the nuclear pore complex. In the presence ofnucleoside triphosphates and the small GTP binding protein Ran, thecomplex moves into the nuclear pore complex and the importinsubunits dissociate. Importin alpha enters the nucleoplasm with itspassenger protein and importin beta remains at the pore.Interactions between importin beta and the FG repeats ofnucleoporins are essential in translocation through the porecomplex. The protein encoded by this gene is a member of theimportin beta family.
Other Names:
Importin-5, Imp5, Importin subunit beta-3, Karyopherin beta-3, Ran-binding protein 5, RanBP5, IPO5, KPNB3, RANBP5
Gene Name: IPO5
Gene ID: 3843
Primary Accession: O00410
Other Accession: NP_002262
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Nucleocytoplasmic transport, a signal- andenergy-dependent process, takes place through nuclear porecomplexes embedded in the nuclear envelope. The import of proteinscontaining a nuclear localization signal (NLS) requires the NLSimport receptor, a heterodimer of importin alpha and beta subunitsalso known as karyopherins. Importin alpha binds the NLS-containingcargo in the cytoplasm and importin beta docks the complex at thecytoplasmic side of the nuclear pore complex. In the presence ofnucleoside triphosphates and the small GTP binding protein Ran, thecomplex moves into the nuclear pore complex and the importinsubunits dissociate. Importin alpha enters the nucleoplasm with itspassenger protein and importin beta remains at the pore.Interactions between importin beta and the FG repeats ofnucleoporins are essential in translocation through the porecomplex. The protein encoded by this gene is a member of theimportin beta family.
Other Names:
Importin-5, Imp5, Importin subunit beta-3, Karyopherin beta-3, Ran-binding protein 5, RanBP5, IPO5, KPNB3, RANBP5
Gene Name: IPO5
Gene ID: 3843
Primary Accession: O00410
Other Accession: NP_002262
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review