RANBP5 antibody (clone 1C4), anti-human, mouse, rat
€435.00
In stock
SKU
AC-AT3561a
Catalog Number: AC-AT3561a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHChttps://www.abcepta.com/products/pdf_download/AT3561a-RANBP5-Antibody-monoclonal-M01">Request Information AC-AT3561a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHChttps://www.abcepta.com/products/pdf_download/AT3561a-RANBP5-Antibody-monoclonal-M01">Request Information AC-AT3561a">Request Information
Background:
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
Other Names:
Importin-5, Imp5, Importin subunit beta-3, Karyopherin beta-3, Ran-binding protein 5, RanBP5, IPO5, KPNB3, RANBP5
Antigen Type:
Recombinant Protein
Gene Name: IPO5
Gene ID: 3843
NCBI Accession: NP_002262.3
Primary Accession: O00410
Other Accession: BC001497
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
Other Names:
Importin-5, Imp5, Importin subunit beta-3, Karyopherin beta-3, Ran-binding protein 5, RanBP5, IPO5, KPNB3, RANBP5
Antigen Type:
Recombinant Protein
Gene Name: IPO5
Gene ID: 3843
NCBI Accession: NP_002262.3
Primary Accession: O00410
Other Accession: BC001497
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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