RanBP9 (clone ), anti-human
€388.00
In stock
SKU
MB0163
Background:
May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B.
Alternative Name:
BPM-L, BPM90, Ran-binding protein M, RanBPM, RanBP7, BPM-L, BPM90, RANBPM, RanBP7
Application Dilution: WB: 1:1000, ICC: 1:100~300, IP: 1:50~100
Specificity: This antibody detects endogenous levels of RanBP9 and does not cross-react with related proteins
Immunogen:
Recombinant full length Human RanBP9.
MW: Predicted band size: 78KDa, Observed band size: 95KDa
Swis Prot.: Q96S59
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Mouse IgG1. Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B.
Alternative Name:
BPM-L, BPM90, Ran-binding protein M, RanBPM, RanBP7, BPM-L, BPM90, RANBPM, RanBP7
Application Dilution: WB: 1:1000, ICC: 1:100~300, IP: 1:50~100
Specificity: This antibody detects endogenous levels of RanBP9 and does not cross-react with related proteins
Immunogen:
Recombinant full length Human RanBP9.
MW: Predicted band size: 78KDa, Observed band size: 95KDa
Swis Prot.: Q96S59
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Mouse IgG1. Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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