RAP1A antibody (clone 30), anti-human
€435.00
In stock
SKU
AC-AT3562a
Catalog Number: AC-AT3562a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT3562a">Request Information
Background:
The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.
Other Names:
Ras-related protein Rap-1A, C21KG, G-22K, GTP-binding protein smg p21A, Ras-related protein Krev-1, RAP1A, KREV1
Antigen Type:
Recombinant Protein
Gene Name: RAP1A
Gene ID: 5906
NCBI Accession: NP_001010935.1;NP_002875.1
Primary Accession: P62834
Other Accession: BC014086
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.
Other Names:
Ras-related protein Rap-1A, C21KG, G-22K, GTP-binding protein smg p21A, Ras-related protein Krev-1, RAP1A, KREV1
Antigen Type:
Recombinant Protein
Gene Name: RAP1A
Gene ID: 5906
NCBI Accession: NP_001010935.1;NP_002875.1
Primary Accession: P62834
Other Accession: BC014086
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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