RAP1A polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6078
Background:
Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Activated by guanine nucleotide-exchange factors (GEF) EPAC and EPAC2 in a cAMP-dependent manner, and GFR.
Alternative Name:
C21KG, G 22K, G-22K, GTP binding protein smg p21A, GTP-binding protein smg p21A, KREV 1, KREV1, RAP 1A, RAP1, RAP1A, RAP1A member of RAS oncogene family, RAP1A, Ras related protein Krev 1, Ras related protein Rap 1A, RAS related protein RAP1A, Ras-related protein Krev-1, Ras-related protein Rap-1A, SMGP21,
Application Dilution: WB: 1:500 - 1:2000
Specificity: RAP1A polyclonal antibody detects endogenous levels of RAP1A protein.
Immunogen:
Recombinant full length Human RAP1A.
MW: ~ 21 kDa
Swis Prot.: P62834
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Activated by guanine nucleotide-exchange factors (GEF) EPAC and EPAC2 in a cAMP-dependent manner, and GFR.
Alternative Name:
C21KG, G 22K, G-22K, GTP binding protein smg p21A, GTP-binding protein smg p21A, KREV 1, KREV1, RAP 1A, RAP1, RAP1A, RAP1A member of RAS oncogene family, RAP1A, Ras related protein Krev 1, Ras related protein Rap 1A, RAS related protein RAP1A, Ras-related protein Krev-1, Ras-related protein Rap-1A, SMGP21,
Application Dilution: WB: 1:500 - 1:2000
Specificity: RAP1A polyclonal antibody detects endogenous levels of RAP1A protein.
Immunogen:
Recombinant full length Human RAP1A.
MW: ~ 21 kDa
Swis Prot.: P62834
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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