RAPGEF1 Blocking Peptide (Center)

RAPGEF1 Blocking Peptide (Center)

€363.00
In stock
SKU
AC-BP21422c
Catalog Number: AC-BP21422c
Size: 500 µg
Datasheet
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Background:
Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.

Other Names:
Rap guanine nucleotide exchange factor 1, CRK SH3-binding GNRP, Guanine nucleotide-releasing factor 2, Protein C3G, RAPGEF1, GRF2

Target/Specificity:
The synthetic peptide sequence is selected from aa 536-549 of HUMAN RAPGEF1

Gene Name: RAPGEF1

Gene ID: 2889
Primary Accession: Q13905
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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