RAPGEF1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS72826
Background:
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Alternative Name:
C3G, GRF2
Application Dilution: WB: 1:500 - 1:2000
Specificity: RAPGEF1 polyclonal antibody detects endogenous levels of RAPGEF1 protein.
Immunogen:
Recombinant protein of human RAPGEF1
MW: Refer to figures
Swis Prot.: Q13905
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Alternative Name:
C3G, GRF2
Application Dilution: WB: 1:500 - 1:2000
Specificity: RAPGEF1 polyclonal antibody detects endogenous levels of RAPGEF1 protein.
Immunogen:
Recombinant protein of human RAPGEF1
MW: Refer to figures
Swis Prot.: Q13905
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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