RAPGEF2 antibody (clone 100000000), anti-human
€435.00
In stock
SKU
AC-AT3566a
Catalog Number: AC-AT3566a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT3566a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT3566a">Request Information
Background:
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM]
Other Names:
Rap guanine nucleotide exchange factor 2, Cyclic nucleotide ras GEF, CNrasGEF, Neural RAP guanine nucleotide exchange protein, nRap GEP, PDZ domain-containing guanine nucleotide exchange factor 1, PDZ-GEF1, RA-GEF-1, Ras/Rap1-associating GEF-1, RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Antigen Type:
Recombinant Protein
Gene Name: RAPGEF2
Gene ID: 9693
NCBI Accession: NP_055062.1
Primary Accession: Q9Y4G8
Other Accession: XM_376350
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM]
Other Names:
Rap guanine nucleotide exchange factor 2, Cyclic nucleotide ras GEF, CNrasGEF, Neural RAP guanine nucleotide exchange protein, nRap GEP, PDZ domain-containing guanine nucleotide exchange factor 1, PDZ-GEF1, RA-GEF-1, Ras/Rap1-associating GEF-1, RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Antigen Type:
Recombinant Protein
Gene Name: RAPGEF2
Gene ID: 9693
NCBI Accession: NP_055062.1
Primary Accession: Q9Y4G8
Other Accession: XM_376350
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review