RARA polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7672
Background:
Retinoic acid receptors (RARalpha, -beta and -gamma) and retinoid X receptors (RXRalpha, -beta and -gamma) are nuclear receptors that function as RAR-RXR heterodimers or RXR homodimers. In response to retinoid binding, these dimers control gene expression by binding to specific retinoic acid response elements, by recruiting cofactors and the transcriptional machinery, and by indirectly regulating chromatin structure. Finally, ligand binding and phosphorylation of RARalpha by JNK at Thr181, Ser445 and Ser461 controls the stability of RAR-RXR through the ubiquitin-proteasome pathway.
Alternative Name:
Acute Promelocytic Leukemia Breakpoint Cluster Region, Acute Promelocytic Leukemia Breakpoint Cluster Region, NR1B1, Nuclear mitotic apparatus protein retinoic acid receptor alpha fusion protein, Nuclear receptor subfamily 1 group B member 1, Nucleophosmin retinoic acid receptor alpha fusion protein NPM RAR long form, RAR A, RAR alpha, RAR alpha, RAR alpha form, RAR alpha form, RAR, RAR-alpha, RARA, RARA, RARA protein, RARA/PML Fusion Gene, RARA/PML Fusion Gene,RARA_HUMAN,RARalpha, RARalpha1, Retinoic acid receptor alpha, Retinoic acid receptor alpha polypeptide,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: RARA polyclonal antibody detects endogenous levels of RARA protein.
Immunogen:
Recombinant full length Human RARA.
MW: ~51 kDa
Swis Prot.: P10276
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Retinoic acid receptors (RARalpha, -beta and -gamma) and retinoid X receptors (RXRalpha, -beta and -gamma) are nuclear receptors that function as RAR-RXR heterodimers or RXR homodimers. In response to retinoid binding, these dimers control gene expression by binding to specific retinoic acid response elements, by recruiting cofactors and the transcriptional machinery, and by indirectly regulating chromatin structure. Finally, ligand binding and phosphorylation of RARalpha by JNK at Thr181, Ser445 and Ser461 controls the stability of RAR-RXR through the ubiquitin-proteasome pathway.
Alternative Name:
Acute Promelocytic Leukemia Breakpoint Cluster Region, Acute Promelocytic Leukemia Breakpoint Cluster Region, NR1B1, Nuclear mitotic apparatus protein retinoic acid receptor alpha fusion protein, Nuclear receptor subfamily 1 group B member 1, Nucleophosmin retinoic acid receptor alpha fusion protein NPM RAR long form, RAR A, RAR alpha, RAR alpha, RAR alpha form, RAR alpha form, RAR, RAR-alpha, RARA, RARA, RARA protein, RARA/PML Fusion Gene, RARA/PML Fusion Gene,RARA_HUMAN,RARalpha, RARalpha1, Retinoic acid receptor alpha, Retinoic acid receptor alpha polypeptide,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: RARA polyclonal antibody detects endogenous levels of RARA protein.
Immunogen:
Recombinant full length Human RARA.
MW: ~51 kDa
Swis Prot.: P10276
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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