RARRES2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8616
Background:
Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells. TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.
Alternative Name:
Retinoic acid receptor responder protein 2, RAR-responsive protein TIG2, Tazarotene-induced gene 2 protein, RARRES2, TIG2, Chemerin
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200, IF: 1:50~1:200
Specificity: RARRES2 polyclonal antibody detects endogenous levels of RARRES2 protein.
Immunogen:
Recombinant full length Human RARRES2.
MW: ~ 18kDa
Swis Prot.: Q99969
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells. TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.
Alternative Name:
Retinoic acid receptor responder protein 2, RAR-responsive protein TIG2, Tazarotene-induced gene 2 protein, RARRES2, TIG2, Chemerin
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200, IF: 1:50~1:200
Specificity: RARRES2 polyclonal antibody detects endogenous levels of RARRES2 protein.
Immunogen:
Recombinant full length Human RARRES2.
MW: ~ 18kDa
Swis Prot.: Q99969
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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