RASA3 antibody (clone 1F11), anti-human
€435.00
In stock
SKU
AC-AT3575a
Catalog Number: AC-AT3575a
Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, E
Request Information AC-AT3575a">Request Information
Background:
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.
Other Names:
Ras GTPase-activating protein 3, GAP1(IP4BP), Ins P4-binding protein, RASA3
Antigen Type:
Recombinant Protein
Gene Name: RASA3
Gene ID: 22821
NCBI Accession: NP_031394.2
Primary Accession: Q14644
Other Accession: BC047242
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.
Other Names:
Ras GTPase-activating protein 3, GAP1(IP4BP), Ins P4-binding protein, RASA3
Antigen Type:
Recombinant Protein
Gene Name: RASA3
Gene ID: 22821
NCBI Accession: NP_031394.2
Primary Accession: Q14644
Other Accession: BC047242
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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